Wireless or wired connection to music server?

[6sigma]

On another forum a user is advocating an HP MediaSmart server and a Squeezebox Duet as the source for an audiophile-quality system. Two questions:

 

1. If a PC/NAS or music server is to be remote from the listening room, are the Squeezebox products the only answer?

 

2. If a PC/NAS or music server is going to be wired to the DAC-Pre-Amp, what's the best cable/connection to use for best sound quality?

 

Thanks.